JR Pass 14 days activation

Hi,

I'm planning to visit Japan for 16 nights in November and I am wondering when it would be best to activate my JR 14 days Pass for my trip.

I will be arriving in Tokyo on Friday November 3rd in the morning. Is it better to activate my pass as soon as I arrive? Or wait a few days before I do because it's more useful at the end of my trip? Maybe activate it on the 6th instead?

My itinerary is as follows

Friday 3/11 Arrive in Tokyo, Explore Tokyo Station area and Shibuya
Saturday 4/11 Ueno Park, Ameyayokocho street, Senso-ji Temple, Akihabara
Sunday 5/11 Tokyo Metropolitan Building, Meiji Shrine, Shinjuku, Happy Pancakes
Monday 6/11 Imperial Palace and East Gardens, Shopping, Ninja Restaurant, Mario Go-Kart
Tuesday 7/11 Leave Tokyo - Go to Hakone
Wednesday 8/11 Leave Hakone - Got o Mount Fuji
Thursday 9/11 Leave Mount Fuji - Go back to Tokyo, Tokyo Shopping + Food + Capsule Experience
Friday 10/11 Leave Tokyo/Arrive in Kyoto - Kiyomizu-dera, ninenzaka and sannenzaka, Yasaka shrine, Maruyama Park, Gion, Kichi Kichi omurice
Saturday 11/11 Arashiyama bamboo forest, Sagano Romantic Train, Kinkakuji Temple
Sunday 12/11 Fushimi Inari Taisha, Nishiki Market, Higashi Hongan-ji Temple, Kyoto Station at Night
Monday 13/11 Day Trip to Nara
Tuesday 14/11 Leave Kyoto - Arrive in Osaka, Shitennoji Temple, Shinsekai
Wednesday 15/11 Osaka Castle, Dotonbori, Shinsaibashi/Ebisubashi, Uncle Rikuro's Cheesecake, Zauo's Fishing Restaurant
Thursday 16/11 Universal Studios
Friday 17/11 Horishima Day Trip
Saturday 18/11 Extra day - Shopping, do any missed activities and might explore having another day trip if possible
Sunday 19/11 Leave from Kansai airport Osaka